Development of a Systems Pharmacology Model Challenge and Win $75,000

Innocentive is offering "Development of a Systems Pharmacology Model" Challenge. Studying the pharmacological effects of drugs injected into the human eye is difficult because traditional sampling methods are invasive. Therefore, the Seeker desires a computational model that accurately simulates the systems pharmacology of an administered drug that requires written documentation, output from the proposed algorithm, and submission of the source code. Novartis is launching a Challenge for a recently introduced drug in the market that is linked with post-marketing adverse event case reports following administration of the drug in the human eye. A small number of patients experienced adverse events termed as “retinal vasculitis” and/or “retinal vascular occlusion” that may result in severe vision loss and/or decreased visual acuity.

Eligibility Criteria:

The submission to the Challenge should include the following:

1. A detailed description of the proposed Solution and how it addresses each Technical Requirement presented in the Detailed Description of the Challenge. 
2. This should also include a thorough description of the algorithm used in the Solution accompanied by a well-articulated rationale for the method employed.
3. A simplified block diagram, with legend, of the systems pharmacology model.
4. Output from the proposed algorithm as applied to specified parameters.
5. For only the top ranked submissions, the Seeker may request the source code and/or an executable with sufficient documentation to enable the Seeker to compile, execute the algorithm, and validate the method using additional internal data.

Awards:

$75,000

About InnoCentive:

InnoCentive is the global leader in crowdsourcing innovation problems to the world’s smartest people who compete to provide ideas and solutions to important business, social, policy, scientific, and technical challenges. Commercial, governmental and humanitarian organizations engage with InnoCentive to solve problems that can impact humankind in areas ranging from the environment to medical advancements. InnoCentive's global network of millions of problem solvers, proven challenge methodology, and cloud-based innovation management platform combine to help its clients transform their economics of innovation through rapid solution delivery and the development of sustainable open innovation programs.

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